Thyroid Eye Disease Specialist
(Graves’ Orbitopathy)

Thyroid eye disease (TED), also known as GO (Graves’ Orbitopathy) is a rare condition that is often very stressful. It can be very difficult to come to terms with, as it involves not only the function and appearance of the eyes but often changes the whole appearance of the face. There are effective medical and surgical treatments for the different stages and types of TED.

The best care is provided by an oculoplastic, ophthalmologist, specialist in TED and an endocrinologist.

Mr Uddin is a leading specialist in thyroid eye disease, with over 20 years of experience in treating this condition. He runs the TED clinic at Moorfield's Eye Hospital, where 5000 thyroid eye disease cases have been treated over 15 years. Mr Uddin has personally performed over 500 orbital decompression procedures in the last 10 years.

Mr Uddin supports education, research and support of TED patients. He is a founding member and former President of the ITEDS (International Thyroid Eye Disease Society), original member of the award-winning TEAMed working group and past chairman of TEDct

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“Thyroid eye disease is a fascinating condition, commonly associated with an overactive thyroid, but this is not always the case… The disease can be split into different categories or ‘phenotypes’ with different drivers and characteristics which respond to treatment in different ways… Symptoms of thyroid eye disease, can be similar to other conditions, requiring expert interpretation of clinical signs and investigations.”

Can Thyroid Eye Disease (TED) be treated?

A patient journey: This is an example of a man presenting with quite severe TED in the active phase. Each patient has their own journey which can sometimes be helped with various treatments at different stages

He presented early with severe, active TED

He presented early with severe, active TED

Following treatment with steroids and radiotherapy.
His left normalised and he had residual prominence of the right eye

Following treatment with steroids and radiotherapy. His left normalised and he had residual prominence of the right eye

He underwent right orbital decompression, achieving a good, symmetrical globe position, with persistent right upper eyelid retraction

He underwent right orbital decompression, achieving a good, symmetrical globe position, with persistent right upper eyelid retraction

He then underwent right upper eyelid lowering surgery

He then underwent right upper eyelid lowering surgery

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Patient with left upper lid retraction treated

What is Thyroid Eye Disease?

“Thyroid eye disease is heterogenous....there are different types or “phenotypes”...with different clinical characteristics..with different ‘drivers’ for disease. It is important to try to differentiate these types as they respond better to the appropriate treatment “

Thyroid eye disease (TED), also known as Graves’ eye disease, is an autoimmune condition in which the fat and muscles around the eye become inflamed. These can expand to cause proptosis (prominent eye pushed forward), eyelid retraction (starey appearance) and double vision (muscles become stiff and don’t move properly). It is more commonly found in Europe and America.

The progression of the disease can be split into three phases.

  1. Early, active ‘wet’ phase (can last 6 to 18 months)
  2. Mid, plateau phase (the disease is stable, can last some months)
  3. Late, “burnout”, ‘dry’ phase (after 12 to 24 months)
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“Thyroid eye disease is heterogenous....there are different types or “phenotypes”...with different clinical characteristics..with different ‘drivers’ for disease. Its important to try to differentiate these types as they respond better to the appropriate treatment.”

Contact us

Moorfields Private Outpatient Centre

9-11 Bath St EC1V 9LF
London (Central London)

Moorfields Private Practice

8 Upper Wimpole St W1G 6LH
London (Central London)

Parkside Hospital

53 Parkside SW19 5NX
London (Wimbledon)

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